Ameloblastin (AMBN) Antibody (HRP)

Este producto es parte de AMBN - Ameloblastin
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169€ (20 µg)

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935106861
info@markelab.com
name
Ameloblastin (AMBN) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx334674
tested applications
ELISA

Description

AMBN Antibody (HRP) is a Rabbit Polyclonal against AMBN.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Ameloblastin (AMBN)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
HRP
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9NP70
Gene ID
258
Alias
AMBN
Background
Antibody anti-AMBN
Status
RUO

Descripción

Ameloblastin, encoded by the AMBN gene, is a protein primarily found in the extracellular matrix of dental tissues, particularly in enamel-forming cells called ameloblasts. It is a major component of the enamel matrix, which is essential for the formation and mineralization of dental enamel, the outer layer of teeth. Ameloblastin plays several important roles in tooth development and enamel formation. Matrix organization: Ameloblastin helps organize the enamel matrix, providing a scaffold for the deposition of mineral crystals during enamel formation. It interacts with other enamel matrix proteins and forms complexes that contribute to the structural integrity of the developing enamel. Mineralization regulation: Ameloblastin participates in the regulation of enamel mineralization by influencing the nucleation and growth of hydroxyapatite crystals, the main mineral component of enamel. It contains specific domains that can bind calcium and phosphate ions, which are essential for the mineralization process. Cell signaling: Ameloblastin can also act as a signaling molecule, influencing the behavior and function of ameloblasts during enamel development. It interacts with cell surface receptors and intracellular signaling pathways, modulating processes such as cell adhesion, proliferation, and differentiation.

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