Ameloblastin (AMBN) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Ameloblastin (AMBN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx323321
tested applications
ELISA, WB
Description
AMBN Antibody is a Rabbit Polyclonal against AMBN.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ameloblastin (AMBN) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NP70 |
| Gene ID | 258 |
| Alias | AMBN |
| Background | Antibody anti-AMBN |
| Status | RUO |
Descripción
Ameloblastin, encoded by the AMBN gene, is a protein primarily found in the extracellular matrix of dental tissues, particularly in enamel-forming cells called ameloblasts. It is a major component of the enamel matrix, which is essential for the formation and mineralization of dental enamel, the outer layer of teeth. Ameloblastin plays several important roles in tooth development and enamel formation. Matrix organization: Ameloblastin helps organize the enamel matrix, providing a scaffold for the deposition of mineral crystals during enamel formation. It interacts with other enamel matrix proteins and forms complexes that contribute to the structural integrity of the developing enamel. Mineralization regulation: Ameloblastin participates in the regulation of enamel mineralization by influencing the nucleation and growth of hydroxyapatite crystals, the main mineral component of enamel. It contains specific domains that can bind calcium and phosphate ions, which are essential for the mineralization process. Cell signaling: Ameloblastin can also act as a signaling molecule, influencing the behavior and function of ameloblasts during enamel development. It interacts with cell surface receptors and intracellular signaling pathways, modulating processes such as cell adhesion, proliferation, and differentiation.
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