Human Alpha-Amylase 2B (AMY2B) ELISA Kit
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Description
Human Alpha-Amylase 2B (AMY2B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-Amylase 2B (AMY2B) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alpha-Amylase 2B (AMY2B) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | < 0.41 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P19961 |
| Gene ID | 280 |
| OMIM | 104660 |
| Alias | AMY2,AMY3,HXA |
| Background | Elisa kits for AMY2B |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AMY2B is a pancreatic alpha-amylase isozyme that shares structural and functional similarity with AMY2A. It is produced in the pancreas and contributes to the hydrolysis of starch and glycogen into absorbable sugars during digestion in the small intestine. AMY2B, along with AMY2A, ensures efficient breakdown of dietary polysaccharides, supporting energy production and metabolic homeostasis. AMY2B levels are frequently assessed alongside AMY2A to evaluate pancreatic health in clinical settings. Elevated AMY2B levels are associated with acute and chronic pancreatitis, pancreatic trauma, and other gastrointestinal disorders. Genetic variations in AMY2B can impact enzyme activity, influencing carbohydrate metabolism and susceptibility to metabolic diseases such as type 2 diabetes and obesity. While AMY2B primarily functions in digestion, it may also play a role in broader metabolic regulation, underscoring its importance in maintaining pancreatic and systemic energy balance.
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Amylases are secreted proteins that hydrolyze 1, 4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.
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