Human Alpha 1A Adrenergic Receptor (ADRA1A) CLIA Kit

Background

The adrenergic receptors are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter adrenaline (epinephrine) and noradrenaline (norepinephrine). The alpha-1 adrenergic receptor (ADRA1) is one subtype of adrenergic receptors, and it has three main subtypes: Alpha-1A (ADRA1A), Alpha-1B (ADRA1B), and Alpha-1D (ADRA1D). ADRA1A is primarily located in vascular smooth muscle cells and plays a role in vasoconstriction, leading to an increase in blood pressure. Activation of ADRA1A receptors can also stimulate smooth muscle contraction in other tissues, such as the bladder and uterus.