Alpha 1A Adrenergic Receptor (ADRA1A) Antibody
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935106861
info@markelab.com
Precio
312€ (60 µl)
Antibody anti-ADRA1A
proveedor
Abbexareference
abx001252Tested Applications
WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
ADRA1A Antibody is a Rabbit Polyclonal antibody against ADRA1A. ADRA1A, also named as ADRA1C, belongs to the G-protein coupled receptor 1 family. ADRA1A mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. The antibody is specific to ADRA1A.
Background
The adrenergic receptors are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter adrenaline (epinephrine) and noradrenaline (norepinephrine). The alpha-1 adrenergic receptor (ADRA1) is one subtype of adrenergic receptors, and it has three main subtypes: Alpha-1A (ADRA1A), Alpha-1B (ADRA1B), and Alpha-1D (ADRA1D). ADRA1A is primarily located in vascular smooth muscle cells and plays a role in vasoconstriction, leading to an increase in blood pressure. Activation of ADRA1A receptors can also stimulate smooth muscle contraction in other tissues, such as the bladder and uterus.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Alpha 1A Adrenergic Receptor (ADRA1A)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC
purification
Purified by affinity chromatography.
recommended dilution
WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
size 1
60 µl
size 2
120 µl
size 3
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ADRA1A
dry ice
No
availability
Shipped within 5-10 working days.
alias
ADRA1A,ADRA1C,ADRA1L1,ALPHA1AAR
uniprot id
NCBI accession
NP_150646.3
note
Concentration: 1 mg/ml -
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