Human Aldolase B, Fructose Bisphosphate (ALDOB) Protein
Pida mas información
935106861
info@markelab.com
Precio
221€ (10 µg)
Protein ALDOB
proveedor
Abbexareference
abx166746Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Aldolase B, Fructose Bisphosphate Protein is a recombinant Human protein expressed in E. coli.
Background
ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Aldolase B, Fructose Bisphosphate (ALDOB)
host
E. coli
conjugation
Unconjugated
form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 41.1 kDa Observed MW (SDS-PAGE): 41 kDa Concentration: Prior to lyophilization: 100 µg/ml Sequence Fragment: Ile19-Tyr364 Tag: N-terminal His tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ALDOB
dry ice
No
availability
Shipped within 5-7 working days.
alias
ALDOB,ALDB
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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