Fructose Bisphosphate Aldolase B (ALDOB) Antibody

312€ (100 µg)
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935106861
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name
Fructose Bisphosphate Aldolase B (ALDOB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx018052
tested applications
ELISA, WB
Description
ALDOB Antibody is a Mouse Monoclonal antibody against ALDOB.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Fructose Bisphosphate Aldolase B (ALDOB) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG2a |
Purification | Purified from ascites by Protein A chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | Citrate-Tris-HCl, pH 7.0, with 0.02% Proclin-300. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
NCBI Accession | NM_000035 |
Alias | ALDOB,ALDB |
Background | Antibody anti-ALDOB |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.
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