Fructose Bisphosphate Aldolase B (ALDOB) Antibody

Este producto es parte de ALDOB - Fructose-Bisphosphate Aldolase B
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312€ (100 µg)

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935106861
info@markelab.com
name
Fructose Bisphosphate Aldolase B (ALDOB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx018052
tested applications
ELISA, WB

Description

ALDOB Antibody is a Mouse Monoclonal antibody against ALDOB.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Fructose Bisphosphate Aldolase B (ALDOB)
Host
Mouse
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG2a
Purification
Purified from ascites by Protein A chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
Citrate-Tris-HCl, pH 7.0, with 0.02% Proclin-300.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NM_000035
Alias
ALDOB,ALDB
Background
Antibody anti-ALDOB
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.

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