Human Alcohol Dehydrogenase 1A (ADH1A) Protein
234€ (5 µg)
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Name
Human Alcohol Dehydrogenase 1A (ADH1A) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx073330
Tested Applications
SDS-PAGE
Description
Alcohol Dehydrogenase 1A is a recombinant enzyme.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Alcohol Dehydrogenase 1A (ADH1A) |
| Host | E. coli |
| Assay Type | Activity: Not tested |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4°C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07327 |
| Alias | ADH1 |
| Background | Protein ADH1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADH1A is a member of the alcohol dehydrogenase (ADH) family, specifically the alpha subunit of the class I ADH enzymes, which are expressed primarily in the liver and gastrointestinal tract. These enzymes catalyze the oxidation of alcohols to aldehydes, playing a central role in the metabolism of ethanol and other substrates such as retinol and hydroxysteroids. ADH1A contributes to the initial step of alcohol metabolism, enabling the conversion of ethanol into acetaldehyde, which is subsequently metabolized by aldehyde dehydrogenase. Its expression is critical for detoxification and energy production pathways. Genetic polymorphisms in ADH1A can affect enzyme activity, influencing an individual's alcohol tolerance and susceptibility to alcohol-related diseases such as liver cirrhosis and alcohol dependence. Beyond ethanol metabolism, ADH1A is also involved in retinoid metabolism, highlighting its broader role in cellular signaling and development.
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