Human Alcohol Dehydrogenase 1 (ADH1) Protein
221€ (10 µg)
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935106861
info@markelab.com
name
Human Alcohol Dehydrogenase 1 (ADH1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065211
tested applications
WB, SDS-PAGE
Description
Human Alcohol Dehydrogenase 1 (ADH1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Alcohol Dehydrogenase 1 (ADH1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 25.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys169-Arg370 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07327 |
| Alias | ADH1 |
| Background | Protein ADH1A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADH1A is a member of the alcohol dehydrogenase (ADH) family, specifically the alpha subunit of the class I ADH enzymes, which are expressed primarily in the liver and gastrointestinal tract. These enzymes catalyze the oxidation of alcohols to aldehydes, playing a central role in the metabolism of ethanol and other substrates such as retinol and hydroxysteroids. ADH1A contributes to the initial step of alcohol metabolism, enabling the conversion of ethanol into acetaldehyde, which is subsequently metabolized by aldehyde dehydrogenase. Its expression is critical for detoxification and energy production pathways. Genetic polymorphisms in ADH1A can affect enzyme activity, influencing an individual's alcohol tolerance and susceptibility to alcohol-related diseases such as liver cirrhosis and alcohol dependence. Beyond ethanol metabolism, ADH1A is also involved in retinoid metabolism, highlighting its broader role in cellular signaling and development.
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