Human Alcohol Dehydrogenase 1 (ADH1) Protein

Este producto es parte de ADH - Alcohol dehydrogenase
Human Alcohol Dehydrogenase 1 (ADH1) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ADH1A

proveedor

Abbexa

reference

abx065211

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Alcohol Dehydrogenase 1 (ADH1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

ADH1A is a member of the alcohol dehydrogenase (ADH) family, specifically the alpha subunit of the class I ADH enzymes, which are expressed primarily in the liver and gastrointestinal tract. These enzymes catalyze the oxidation of alcohols to aldehydes, playing a central role in the metabolism of ethanol and other substrates such as retinol and hydroxysteroids. ADH1A contributes to the initial step of alcohol metabolism, enabling the conversion of ethanol into acetaldehyde, which is subsequently metabolized by aldehyde dehydrogenase. Its expression is critical for detoxification and energy production pathways. Genetic polymorphisms in ADH1A can affect enzyme activity, influencing an individual's alcohol tolerance and susceptibility to alcohol-related diseases such as liver cirrhosis and alcohol dependence. Beyond ethanol metabolism, ADH1A is also involved in retinoid metabolism, highlighting its broader role in cellular signaling and development.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Alcohol Dehydrogenase 1 (ADH1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 25.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys169-Arg370 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ADH1A


dry ice

No


availability

Shipped within 5-7 working days.


alias

ADH1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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WB, SDS-PAGE

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Human Alcohol Dehydrogenase 1 (ADH1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli...

221€ (10 µg)

Ver más