Human AKAP17A (A-kinase anchor protein 17A) ELISA Kit

Product specifications

ELISA Kits

Human

Colorimetric

4 hours

Sandwich ELISA, Double Antibody

0.156-10ng/ml

0.094ng/ml

96T

ELISA

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Shipped within 10-14 working days.

2-8 °C for 12 months

Q02040

721P,AKAP-17A,CCDC133

Elisa kits for AKAP17A

RUO

AKAP17A, also known as S-AKAP84, is a mitochondrial scaffold protein that binds PKA and regulates mitochondrial function, including ATP production and apoptosis. AKAP17A primarily anchors PKA to the mitochondrial membrane, facilitating cAMP-dependent signaling pathways that control oxidative phosphorylation and energy homeostasis. It has a role in maintaining mitochondrial integrity during cellular stress by regulating apoptosis signaling, including interactions with pro- and anti-apoptotic proteins like Bcl-2 and caspases. AKAP17A is expressed in tissues with high energy demands, such as cardiac and skeletal muscle, where it enhances mitochondrial respiration. Dysregulation of AKAP17A impairs mitochondrial dynamics, contributing to metabolic disorders, neurodegeneration, and cardiovascular diseases. AKAP17A has also been shown to interact with mitochondrial DNA-binding proteins, influencing mitochondrial biogenesis and replication under stress conditions.

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