Human AIMP1 (Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1) ELISA Kit
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Name
Human AIMP1 (Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH2608
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 125-8000pg/ml |
| Sensitivity | 75pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q12904 |
| Alias | p43,HLD3,EMAP2,SCYE1,EMAPII |
| Background | Elisa kits for AIMP1 |
| Status | RUO |
Background
AIMP1, also known as EMAP II (Endothelial Monocyte-Activating Polypeptide II), is a multifunctional protein that acts as a core component of the multi-aminoacyl-tRNA synthetase complex (MSC), which is essential for protein synthesis. It interacts with various aminoacyl-tRNA synthetases to maintain the stability and functionality of the complex. Beyond its role in translation, AIMP1 has extracellular signaling functions, particularly in modulating immune responses and angiogenesis. When secreted, AIMP1 functions as a cytokine that activates monocytes and endothelial cells, contributing to inflammatory responses and tissue repair. It is also involved in apoptosis, cellular stress responses, and tumor suppression. Dysregulation of AIMP1 is associated with cancer progression, inflammatory diseases, and autoimmune disorders, highlighting its dual roles in intracellular protein synthesis and extracellular signaling.
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