Human Adrenocortical Dysplasia Homolog (ACD) ELISA Kit

Este producto es parte de ACD - Adrenocortical Dysplasia Homolog
Human Adrenocortical Dysplasia Homolog (ACD) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

546€ (96 tests)

Elisa kits for ACD

proveedor

Abbexa

reference

abx354310

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Adrenocortical Dysplasia Homolog (ACD) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adrenocortical Dysplasia Homolog (ACD) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ACD, also known as TPP1, is a shelterin complex component involved in protecting telomeres and maintaining chromosomal stability. It regulates telomere length and integrity by recruiting telomerase and interacting with other shelterin proteins, such as POT1, to prevent inappropriate DNA damage responses at chromosome ends. ACD plays a critical role in cellular aging, genome stability, and cancer suppression. It is expressed in proliferative tissues, where telomere maintenance is essential for cellular replication. Dysregulation or mutations in ACD are associated with telomere-related disorders, such as dyskeratosis congenita and aplastic anemia, as well as increased susceptibility to cancer due to compromised chromosomal stability. ACD’s functions in telomere biology underscore its importance in aging, genome integrity, and disease prevention.

Características del producto

category

ELISA Kits


immunogen target

Adrenocortical Dysplasia Homolog (ACD)


reactivity

Human


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

18.8 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ACD,PIP1,PTOP,TINT1,TPP1,adrenocortical dysplasia homolog shelterin complex subunit and telomerase recruitment factor


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ACD


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

anti- ACD antibody

anti- ACD antibody

proveedor

FineTest

reference

FNab00078

Tested Applications

ELISA, WB

reactivity

human

status

RUO

clonality

polyclonal

Component of the shelterin complex(telosome) that is involved in the regulation of telomere length and protection. Shelt...

Precio a consultar

Ver más

Adrenocortical Dysplasia Homolog (ACD) Antibody

Adrenocortical Dysplasia Homolog (ACD) Antibody

proveedor

Abbexa

reference

abx038018

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Rabbit Polyclonal against the ACD protein.

357.5€ (100 µg)

Ver más

Adrenocortical Dysplasia Homolog (ACD) Antibody

Adrenocortical Dysplasia Homolog (ACD) Antibody

proveedor

Abbexa

reference

abx125486

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

ACD Antibody is a Rabbit Polyclonal against ACD.

195€ (20 µl)

Ver más