Human ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 1 (ARFGEF1) ELISA Kit

Name: Human ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 1 (ARFGEF1) ELISA Kit
Brand: Abbexa
SKU: abx384554
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de ARFGEF - ADP ribosylation factor guanine nucleotide exchange factor

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ARFGEF1

proveedor

Abbexa

reference

abx384554

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 1 (ARFGEF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ARFGEF1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

ADP ribosylation factor guanine nucleotide exchange factor 1 (ARFGEF1) is a protein that regulates ADP-ribosylation factor (ARF) proteins, which are involved in the regulation of vesicular trafficking, actin cytoskeleton dynamics, and cell signaling ARFGEF1 acts as a guanine nucleotide exchange factor (GEF) that activates ARF proteins by facilitating the exchange of GDP for GTP, a process crucial for ARF-mediated signaling In addition to regulating vesicle trafficking in cellular processes like endocytosis and exocytosis, ARFGEF1 influences the organization of the actin cytoskeleton, which is important for cellular motility, morphology, and division It is involved in processes such as receptor internalization, membrane trafficking, and the formation of specialized membrane domains Disruptions in ARFGEF1 can lead to defects in vesicular trafficking, cell adhesion, and immune responses, and it has been implicated in diseases such as cancer, where altered cell signaling and vesicle trafficking contribute to uncontrolled cell growth and metastasis ARFGEF1 also represents a potential therapeutic target for diseases related to cellular trafficking and actin dynamics, such as cancer and neurodegenerative diseases

Características del producto

immunogen target

ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 1 (ARFGEF1)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

sensitivity

< 0.094 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

alias

BIG1,P200,DEDISB,ARFGEP1,p200 ARF guanine nucleotide exchange factor,Brefeldin A-inhibited GEP 1,Brefeldin A-inhibited guanine nucleotide-exchange protein 1

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

ARFGEF1

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q9Y6D6

gene id

https://www.ncbi.nlm.nih.gov/gene/10565

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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