Human Adhesion Molecule With Ig Like Domain 3 (AMIGO3) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Adhesion Molecule With Ig Like Domain 3 (AMIGO3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385729
tested applications
ELISA
Description
Human Adhesion Molecule With Ig Like Domain 3 (AMIGO3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adhesion Molecule With Ig Like Domain Protein 3 (AMIGO3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Adhesion Molecule With Ig Like Domain 3 (AMIGO3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q86WK7 |
| Gene ID | 386724 |
| OMIM | 615691 |
| Alias | AMIGO3,ALI3,Alivin-3 |
| Background | Elisa kits for AMIGO3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AMIGO3 is a member of the AMIGO family that primarily functions in cell adhesion, neuronal development, and cell survival signaling. It is expressed in the central nervous system, where it regulates axon guidance and myelination during neural development. AMIGO3 interacts with other adhesion molecules and extracellular ligands to modulate axon extension and fasciculation, contributing to the formation of functional neural networks. Beyond its role in neural development, AMIGO3 has been implicated in promoting neuronal apoptosis in response to injury or stress, particularly in neuroinflammatory and neurodegenerative conditions. It has also been linked to tumor progression, where it enhances cancer cell survival, migration, and invasion. AMIGO3 is involved in activating signaling pathways such as NF-κB and PI3K/AKT, which support cell survival and inflammatory responses. Its involvement in both neural apoptosis and cancer progression highlights AMIGO3 as a critical player in cellular signaling pathways related to survival and disease.
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