Human Adenylate Kinase 4, Mitochondrial (AK4) Protein
234€ (5 µg)
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Name
Human Adenylate Kinase 4, Mitochondrial (AK4) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx073481
Tested Applications
SDS-PAGE
Description
Adenylate Kinase 4 Protein is a recombinant protein kinases.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Adenylate Kinase 4, Mitochondrial (AK4) |
| Host | E. coli |
| Assay Type | Activity: Not tested |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4°C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P27144 |
| Alias | AK4,AK3,AK3L1,AK3L2 |
| Background | Protein AK4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AK4, also localized in the mitochondrial matrix, is a catalytically inactive adenylate kinase homolog involved in stress response and ATP metabolism regulation. Despite lacking enzymatic activity, AK4 interacts with other AK isoforms to regulate energy homeostasis under stress conditions, including hypoxia or metabolic reprogramming. AK4 expression is elevated in some cancers, suggesting a role in tumor progression and survival. It functions in modulating mitochondrial dynamics and improving resistance to oxidative stress, particularly in high-metabolic tissues like the heart. AK4 has also been linked to cellular signaling pathways regulating apoptosis, energy metabolism, and DNA repair.
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