Human Adenylate Kinase 3 (AK3) ELISA Kit

Este producto es parte de AK - Adenylate kinase
Human Adenylate Kinase 3 (AK3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AK3

proveedor

Abbexa

reference

abx150566

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Adenylate Kinase 3 (AK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adenylate Kinase 3 concentrations in serum, plasma, cerebrospinal fluid and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Adenylate Kinase 3 (AK3)


Background

AK3 is localized within the mitochondrial matrix and utilizes GTP as a phosphate donor instead of ATP, distinguishing it from other AK isoforms. AK3 primarily supports mitochondrial nucleotide exchange, particularly during periods of cellular energy stress. It is abundant in tissues with high-energy demands, such as the brain, liver, and kidneys. AK3 contributes to mitochondrial respiration by facilitating ADP recycling necessary for oxidative phosphorylation. Knockout studies demonstrate that AK3 deficiency disrupts ATP synthesis and exacerbates oxidative stress, which can contribute to neurodegenerative conditions. AK3 has also been implicated in regulating mitochondrial dynamics and maintaining redox balance.

Características del producto

category

ELISA Kits


immunogen target

Adenylate Kinase 3 (AK3)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.15 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, cerebrospinal fluid and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

AK3L1,AK6,AKL3L


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AK3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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