Human Adenylate Cyclase 6 (ADCY6) Protein
221€ (10 µg)
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Name
Human Adenylate Cyclase 6 (ADCY6) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx065157
Tested Applications
WB, SDS-PAGE
Description
Human Adenylate Cyclase 6 (ADCY6) is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Adenylate Cyclase 6 (ADCY6) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Val246-Gly435 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 25.5 kDa Observed MW (SDS-PAGE): 26 kDa |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43306 |
| Alias | AC6,LCCS8,Adenylate cyclase type 6 |
| Background | Protein ADCY6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
ADCY6 is a transmembrane enzyme expressed abundantly in the cardiovascular system and kidneys. It is essential for cAMP production in response to G-protein-coupled receptor activation and is regulated by mechanical stimuli and forskolin. ADCY6 plays a key role in cardiac contraction, vascular smooth muscle relaxation, and renal water regulation. Disruption of ADCY6 function has been associated with cardiovascular diseases, including hypertension and heart failure, due to impaired cAMP-mediated signaling pathways in cardiac tissues.
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