Adenylate Cyclase 6 (ADCY6) Antibody
357.5€ (100 µg)
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Name
Adenylate Cyclase 6 (ADCY6) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx038424
Tested Applications
ELISA, WB
Description
Rabbit Polyclonal against the ADCY6 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase 6 (ADCY6) Immunogen: A peptide corresponding to the N-terminal region of human ADCY6 protein. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 110-130 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_015270 |
| Alias | AC6,LCCS8,Adenylate cyclase type 6 |
| Background | Antibody anti-ADCY6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY6 is a transmembrane enzyme expressed abundantly in the cardiovascular system and kidneys. It is essential for cAMP production in response to G-protein-coupled receptor activation and is regulated by mechanical stimuli and forskolin. ADCY6 plays a key role in cardiac contraction, vascular smooth muscle relaxation, and renal water regulation. Disruption of ADCY6 function has been associated with cardiovascular diseases, including hypertension and heart failure, due to impaired cAMP-mediated signaling pathways in cardiac tissues.
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