Adenylate Cyclase 6 (ADCY6) Antibody

Background

ADCY6 is a transmembrane enzyme expressed abundantly in the cardiovascular system and kidneys. It is essential for cAMP production in response to G-protein-coupled receptor activation and is regulated by mechanical stimuli and forskolin. ADCY6 plays a key role in cardiac contraction, vascular smooth muscle relaxation, and renal water regulation. Disruption of ADCY6 function has been associated with cardiovascular diseases, including hypertension and heart failure, due to impaired cAMP-mediated signaling pathways in cardiac tissues.