Human Adenylate Cyclase 5 (ADCY5) Protein
221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Adenylate Cyclase 5 (ADCY5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065156
tested applications
WB, SDS-PAGE
Description
Human Adenylate Cyclase 5 (ADCY5) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Adenylate Cyclase 5 (ADCY5) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 28.4 kDa Observed MW (SDS-PAGE): 28 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gly167-Glu385 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95622 |
| Gene ID | 111 |
| OMIM | 600293 |
| Alias | AC5, DSKOD, FDFM |
| Background | Protein ADCY5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADCY5 is a G-protein-regulated, membrane-bound enzyme highly expressed in the heart and brain. It is critical for cardiac function, including regulating heart rate and contractility through cAMP production. In the brain, ADCY5 mediates dopamine signaling and contributes to motor control. Mutations in ADCY5 have been linked to familial dyskinesia and neurological movement disorders. It is also implicated in cardiac pathologies, such as heart failure, due to its central role in cAMP-dependent signaling in cardiomyocytes.
Related Products
Adenylate Cyclase Type 5/6 (ADCY5/6) Antibody
Rabbit polyclonal antibody against ADCY5/6 protein. Immunogen region is C-terminal.
Ver Producto
Adenylate Cyclase Type 5/6 (ADCY5/6) Antibody
Rabbit polyclonal antibody against ADCY5/6 protein. Immunogen region is C-terminal.
Ver Producto
Human Adenylate Cyclase 5 (ADCY5) Protein
Human Adenylate Cyclase 5 (ADCY5) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto