Human Adenylate Cyclase 2, Brain (ADCY2) Protein

Este producto es parte de ADCY - Adenylate Cyclase Type
Human Adenylate Cyclase 2, Brain (ADCY2) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein ADCY2

proveedor

Abbexa

reference

abx065152

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Adenylate Cyclase 2, Brain (ADCY2) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

ADCY2 is a transmembrane enzyme expressed widely in the central nervous system and cardiac tissues. It is activated by Gαs proteins and regulated by forskolin and calcium signaling. ADCY2 plays a central role in converting ATP to cAMP, which mediates various cellular responses, including neurotransmission, hormone signaling, and metabolism. It is particularly important in modulating synaptic communication and neuronal excitability. Mutations or alterations in ADCY2 expression have been associated with mood disorders, including schizophrenia and bipolar disorder, highlighting its significance in brain function.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Adenylate Cyclase 2, Brain (ADCY2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 29.6 kDa Observed MW (SDS-PAGE): 31 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala294-Thr525 Tag: N-terminal His tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ADCY2


dry ice

No


availability

Shipped within 5-7 working days.


alias

AC2,HBAC2,ATP pyrophosphate-lyase 2


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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