Human Adenylate Cyclase 2, Brain (ADCY2) CLIA Kit
845€ (96 tests)
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name
Human Adenylate Cyclase 2, Brain (ADCY2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492725
tested applications
CLIA
Description
Human ADCY2 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Adenylate Cyclase 2, Brain (ADCY2) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.126 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AC2,HBAC2,ATP pyrophosphate-lyase 2 |
| Background | CLIA Kits ADCY2 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADCY2 is a transmembrane enzyme expressed widely in the central nervous system and cardiac tissues. It is activated by Gαs proteins and regulated by forskolin and calcium signaling. ADCY2 plays a central role in converting ATP to cAMP, which mediates various cellular responses, including neurotransmission, hormone signaling, and metabolism. It is particularly important in modulating synaptic communication and neuronal excitability. Mutations or alterations in ADCY2 expression have been associated with mood disorders, including schizophrenia and bipolar disorder, highlighting its significance in brain function.
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