Human Adenosylhomocysteinase Like 1 (AHCYL1) ELISA Kit
715€ (96 tests)
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name
Human Adenosylhomocysteinase Like 1 (AHCYL1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx555866
tested applications
ELISA
Description
Human Adenosylhomocysteinase Like 1 (AHCYL1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Putative adenosylhomocysteinase 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Adenosylhomocysteinase Like 1 (AHCYL1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O43865 |
| Alias | DCAL,IRBIT,PPP1R78 |
| Background | Elisa kits for AHCYL1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AHCYL1, also known as inositol 1,4,5-triphosphate receptor binding protein (IRBIT), is structurally similar to AHCY but lacks catalytic activity. Instead, it functions as a regulator of calcium signaling and ion transport. AHCYL1 binds to inositol 1,4,5-triphosphate receptors (IP3Rs), modulating calcium release from the endoplasmic reticulum (ER), and interacts with transporters such as the sodium-bicarbonate cotransporter (NBCe1) to regulate intracellular pH and bicarbonate levels. It is expressed in various tissues, including the kidneys, brain, and pancreas, where it influences processes such as fluid secretion, neuronal excitability, and electrolyte balance. Dysregulation of AHCYL1 has been linked to diseases such as kidney disorders, neurodegenerative diseases, and cystic fibrosis, highlighting its importance in calcium and ion homeostasis.
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