Human ADAMTS-Like Protein 1 (ADAMTSL1) Protein

Este producto es parte de ADAMTSL - ADAMTS-like protein
Product Graph
637€ (20 µg)

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935106861
info@markelab.com
name
Human ADAMTS-Like Protein 1 (ADAMTSL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692492
tested applications
SDS-PAGE

Description

Human ADAMTSL1 Protein is a recombinant protein from Human produced in Baculovirus-Insect Cells. A DNA sequence encoding the human ADAMTSL1 (Met 1-His439) (Q8N6G6-2) was expressed, with a C-terminal polyhistidine tag.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
ADAMTSL1
Host
Insect
Origin
Human
Observed MW
Molecular Weight: 47 kDa
Sequence Fragment: Met1-His439
Tag: C-terminal His tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 97% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Form
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8N6G6-2
Alias
Punctin-1,ADAMTSL-1
Background
Protein ADAMTSL1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADAMTSL1 is a member of the ADAMTS-like (ADAMTSL) protein family, which is structurally related to the ADAMTS proteases but lacks catalytic activity due to the absence of the metalloproteinase domain. ADAMTSL1 is characterized by thrombospondin type 1 repeats (TSRs) and cysteine-rich domains. It is primarily involved in the assembly and regulation of extracellular matrix (ECM) components, particularly fibrillin microfibrils, which are crucial for maintaining tissue integrity and elasticity. Dysregulation of ADAMTSL1 has been associated with connective tissue disorders and ECM-related diseases. Research suggests that ADAMTSL1 may modulate transforming growth factor-beta (TGF-β) signaling pathways, which play essential roles in cellular proliferation and differentiation.
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