ADAMTS Like 1 (ADAMTSL1) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
ADAMTS Like 1 (ADAMTSL1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211509
tested applications
ELISA, IHC
Description
ADAMTSL1 Antibody is a Rabbit Polyclonal against ADAMTSL1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ADAMTS Like 1 (ADAMTSL1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/15 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N6G6 |
| Gene ID | 92949 |
| Alias | Punctin-1,ADAMTSL-1 |
| Background | Antibody anti-ADAMTSL1 |
| Status | RUO |
Descripción
ADAMTSL1 is a member of the ADAMTS-like (ADAMTSL) protein family, which is structurally related to the ADAMTS proteases but lacks catalytic activity due to the absence of the metalloproteinase domain. ADAMTSL1 is characterized by thrombospondin type 1 repeats (TSRs) and cysteine-rich domains. It is primarily involved in the assembly and regulation of extracellular matrix (ECM) components, particularly fibrillin microfibrils, which are crucial for maintaining tissue integrity and elasticity. Dysregulation of ADAMTSL1 has been associated with connective tissue disorders and ECM-related diseases. Research suggests that ADAMTSL1 may modulate transforming growth factor-beta (TGF-β) signaling pathways, which play essential roles in cellular proliferation and differentiation.
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