ADAMTS-Like Protein 1 (ADAMTSL1) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
ADAMTS-Like Protein 1 (ADAMTSL1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005893
tested applications
ELISA, WB
Description
ADAMTSL1 Antibody is a Rabbit Polyclonal Antibody against ADAMTSL1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ADAMTS-Like Protein 1 (ADAMTSL1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N6G6 |
| Gene ID | 92949 |
| NCBI Accession | NP_001035362.3 |
| Alias | Punctin-1,ADAMTSL-1 |
| Background | Antibody anti-ADAMTSL1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
ADAMTSL1 is a member of the ADAMTS-like (ADAMTSL) protein family, which is structurally related to the ADAMTS proteases but lacks catalytic activity due to the absence of the metalloproteinase domain. ADAMTSL1 is characterized by thrombospondin type 1 repeats (TSRs) and cysteine-rich domains. It is primarily involved in the assembly and regulation of extracellular matrix (ECM) components, particularly fibrillin microfibrils, which are crucial for maintaining tissue integrity and elasticity. Dysregulation of ADAMTSL1 has been associated with connective tissue disorders and ECM-related diseases. Research suggests that ADAMTSL1 may modulate transforming growth factor-beta (TGF-β) signaling pathways, which play essential roles in cellular proliferation and differentiation.
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