Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7 (ADAMTS7) ELISA Kit

585€ (96 tests)
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935106861
info@markelab.com
name
Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7 (ADAMTS7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251352
tested applications
ELISA
Description
Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7 (ADAMTS7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7 (ADAMTS7) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7 (ADAMTS7) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.31 ng/ml - 20 ng/ml |
| Sensitivity | 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9UKP4 |
| Gene ID | 11173 |
| OMIM | 605009 |
| Alias | COMPase, Type 1 Motif 7,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7,ADAMTS-7,ADAM-TS 7 |
| Background | Elisa Kits for: ADAMTS7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
ADAMTS7 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 7) is another member of the ADAMTS family of proteases. Like other ADAMTS proteins, ADAMTS7 contains multiple domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS7 is expressed in various tissues, including skeletal muscle, heart, brain, and cartilage. Its expression pattern suggests roles in tissue development, maintenance, and homeostasis. ADAMTS7 is implicated in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS7 has been linked to angiogenesis, inflammation, and wound healing.Dysregulation of ADAMTS7 has been associated with several diseases and conditions. In particular, ADAMTS7 has been implicated in osteoarthritis, where it may contribute to cartilage degradation and joint inflammation. Studies have also linked ADAMTS7 to atherosclerosis, where it may play a role in plaque formation and vascular remodeling.
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