Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 6 (ADAMTS6) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADAMTS6
proveedor
Abbexareference
abx576660Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 6 (ADAMTS6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAMTS6 concentrations in serum, plasma, tissue homogenates and other biological fluids.
Background
ADAMTS6 ,A Disintegrin And Metalloproteinase with Thrombospondin Motifs 6 is a member of the ADAMTS (ADAM with thrombospondin motifs) family of proteases. ADAMTS6 belongs to a group of multidomain proteases characterized by the presence of a metalloproteinase domain, a disintegrin-like domain, and various thrombospondin type-1 (TSP-1) motifs. ADAMTS6 is expressed in various tissues, including skeletal muscle, heart, brain, kidney, and lung. Its expression pattern suggests potential roles in tissue development and homeostasis.ADAMTS6 has been implicated in several physiological and pathological processes. Studies suggest its involvement in ECM remodeling, particularly in the degradation and processing of proteoglycans and other ECM components. It may also play roles in angiogenesis, wound healing, and inflammation.Dysregulation of ADAMTS6 has been implicated in various diseases. For example, altered expression of ADAMTS6 has been reported in cancers, such as breast cancer, where it may influence tumor progression and metastasis. Additionally, mutations in the ADAMTS6 gene have been linked to certain genetic disorders and developmental abnormalities.
Características del producto
category
ELISA Kits
immunogen target
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 6 (ADAMTS6)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 6,ADAM-TS 6,ADAMTS-6
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADAMTS6
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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