Human Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ACOT8
proveedor
Abbexareference
abx500832Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-coenzyme A thioesterase 8 (ACOT8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACOT8 is a ubiquitously expressed peroxisomal enzyme that hydrolyzes a wide range of acyl-CoA substrates, from short- to long-chain fatty acids, contributing to diverse metabolic processes. It plays a vital role in peroxisomal β-oxidation, bile acid synthesis, and the detoxification of reactive lipid intermediates. ACOT8 is particularly active in tissues such as the liver, kidney, and adrenal glands, where it regulates lipid and energy metabolism under conditions of metabolic stress or dietary changes. It also modulates the availability of CoA, ensuring the proper functioning of CoA-dependent enzymes within peroxisomes. Dysregulation of ACOT8 activity has been implicated in metabolic syndromes, including obesity and non-alcoholic fatty liver disease, where altered lipid metabolism affects systemic energy balance. Its broad substrate specificity and enzymatic versatility make ACOT8 a critical player in maintaining peroxisomal and cellular metabolic homeostasis.
Características del producto
category
ELISA Kits
immunogen target
Acyl-coenzyme A thioesterase 8 (ACOT8)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
hTE,NAP1,PTE1,PTE2,PTE-1,PTE-2,HNAACTE,hACTE-III
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ACOT8
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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