Human Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500832
tested applications
ELISA
Description
Human Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-coenzyme A thioesterase 8 (ACOT8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acyl-coenzyme A thioesterase 8 (ACOT8) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O14734 |
| Gene ID | 10005 |
| OMIM | 608123 |
| Alias | hTE,NAP1,PTE1,PTE2,PTE-1,PTE-2,HNAACTE,hACTE-III |
| Background | Elisa kits for ACOT8 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACOT8 is a ubiquitously expressed peroxisomal enzyme that hydrolyzes a wide range of acyl-CoA substrates, from short- to long-chain fatty acids, contributing to diverse metabolic processes. It plays a vital role in peroxisomal β-oxidation, bile acid synthesis, and the detoxification of reactive lipid intermediates. ACOT8 is particularly active in tissues such as the liver, kidney, and adrenal glands, where it regulates lipid and energy metabolism under conditions of metabolic stress or dietary changes. It also modulates the availability of CoA, ensuring the proper functioning of CoA-dependent enzymes within peroxisomes. Dysregulation of ACOT8 activity has been implicated in metabolic syndromes, including obesity and non-alcoholic fatty liver disease, where altered lipid metabolism affects systemic energy balance. Its broad substrate specificity and enzymatic versatility make ACOT8 a critical player in maintaining peroxisomal and cellular metabolic homeostasis.
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