Human Acyl-coenzyme A thioesterase 4 (ACOT4) ELISA Kit
715€ (96 tests)
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name
Human Acyl-coenzyme A thioesterase 4 (ACOT4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500827
tested applications
ELISA
Description
Human Acyl-coenzyme A thioesterase 4 (ACOT4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-coenzyme A thioesterase 4 (ACOT4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acyl-coenzyme A thioesterase 4 (ACOT4) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8N9L9 |
| OMIM | 614314 |
| Alias | PTE1B,PTE2B,PTE-Ib |
| Background | Elisa kits for ACOT4 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACOT4 is a peroxisomal enzyme that hydrolyzes medium- and long-chain acyl-CoA esters into free fatty acids and CoA, contributing to the regulation of peroxisomal β-oxidation and lipid metabolism. It is expressed in tissues involved in lipid processing, such as the liver and kidney, where it participates in detoxifying acyl-CoA intermediates and modulating lipid signaling pathways. ACOT4 plays a key role in the breakdown of branched-chain fatty acids and bile acid intermediates, processes essential for maintaining cellular lipid homeostasis. By regulating the levels of peroxisomal CoA and free fatty acids, ACOT4 influences cellular metabolic efficiency and prevents lipid toxicity. Dysregulation of ACOT4 has been implicated in metabolic syndromes and fatty acid-related disorders, emphasizing its role in maintaining peroxisomal and systemic lipid balance. Its enzymatic function supports metabolic adaptability during dietary shifts and stress conditions, underscoring its importance in lipid metabolism and cellular homeostasis.
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