Human Acyl-CoA Thioesterase 2 (ACOT2) ELISA Kit
715€ (96 tests)
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name
Human Acyl-CoA Thioesterase 2 (ACOT2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385582
tested applications
ELISA
Description
Human Acyl-CoA Thioesterase 2 (ACOT2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl Coenzyme A Thioesterase 2 (ACOT2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acyl-CoA Thioesterase 2 (ACOT2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P49753 |
| Gene ID | 10965 |
| OMIM | 609972 |
| Alias | MTE1,PTE2,CTE1A,PTE2A,CTE-IA,ZAP128 |
| Background | Elisa kits for ACOT2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACOT2 is a mitochondrial enzyme that catalyzes the hydrolysis of acyl-CoA esters into free fatty acids and CoA, playing a pivotal role in mitochondrial fatty acid metabolism and energy regulation. It is highly expressed in energy-demanding tissues such as the heart, liver, and skeletal muscle, where it regulates the pool of acyl-CoA intermediates and ensures efficient β-oxidation. ACOT2 also serves as a key regulator of mitochondrial CoA homeostasis, preventing the accumulation of acyl-CoA esters that could inhibit mitochondrial enzymes. Its role extends to regulating lipid signaling molecules and providing precursors for membrane biosynthesis. Dysregulation of ACOT2 has been associated with metabolic dysfunctions, such as insulin resistance and mitochondrial disorders, reflecting its importance in maintaining energy balance and metabolic integrity. ACOT2’s mitochondrial localization and activity highlight its critical role in coordinating lipid utilization and energy production under various physiological conditions.
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