Human Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) Protein

234€ (2 µg)
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935106861
info@markelab.com
name
Human Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073808
tested applications
SDS-PAGE
Description
ACADSB Protein is a recombinant enzyme.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) |
Host | E. coli |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Origin | Human |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 2 µg |
Size 2 | 10 µg |
Size 3 | 1 mg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P45954 |
Alias | 2-MEBCAD,ACAD7,SBCAD |
Background | Protein ACADSB |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
The ACADSB gene encodes the enzyme short/branched chain specific acyl-CoA dehydrogenase (SBCAD), which belongs to the acyl-CoA dehydrogenase family. This enzyme is involved in catalyzing the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branched-chain amino acids. ACADSB deficiency can lead to short/branched-chain acyl-CoA dehydrogenase deficiency. The enzyme exhibits substrate specificity towards short branched-chain acyl-CoA derivatives, particularly (S)-2-methylbutyryl-CoA, although it also reacts with other 2-methyl branched chain substrates and short straight chain acyl-CoAs. The encoded protein is initially produced as a mitochondrial precursor, which undergoes cleavage upon import into the mitochondria, resulting in a mature peptide of approximately 43.7 kDa.
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