Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) Antibody

Este producto es parte de ACADSB - Acyl-CoA Dehydrogenase, Short/Branched Chain
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038002
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the ACADSB protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by Protein A/G column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, IHC
Buffer
Prior to lyophilization: 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
2-MEBCAD,ACAD7,SBCAD
Background
Antibody anti-ACADSB
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

The ACADSB gene encodes the enzyme short/branched chain specific acyl-CoA dehydrogenase (SBCAD), which belongs to the acyl-CoA dehydrogenase family. This enzyme is involved in catalyzing the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branched-chain amino acids. ACADSB deficiency can lead to short/branched-chain acyl-CoA dehydrogenase deficiency. The enzyme exhibits substrate specificity towards short branched-chain acyl-CoA derivatives, particularly (S)-2-methylbutyryl-CoA, although it also reacts with other 2-methyl branched chain substrates and short straight chain acyl-CoAs. The encoded protein is initially produced as a mitochondrial precursor, which undergoes cleavage upon import into the mitochondria, resulting in a mature peptide of approximately 43.7 kDa.

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