Human Actin-like protein 6B (ACTL6B) ELISA Kit
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Description
Human Actin-like protein 6B (ACTL6B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Actin-like protein 6B (ACTL6B) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Actin-like protein 6B (ACTL6B) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O94805 |
| Gene ID | 51412 |
| Alias | ACTL6,BAF53B,DEE76,EIEE76,IDDSSAD |
| Background | Elisa kits for ACTL6B |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACTL6B, or BAF53B, is a paralog of ACTL6A and functions primarily in post-mitotic neurons. Like ACTL6A, ACTL6B is part of the SWI/SNF chromatin remodeling complex but is specifically associated with neuronal differentiation and synaptic plasticity. Its structure includes conserved ATP-binding motifs and an actin-like fold, contributing to chromatin interactions. ACTL6B is essential for proper neural circuitry development, as it modulates activity-dependent gene expression. Mutations in ACTL6B have been implicated in neurodevelopmental disorders, including intellectual disabilities and autism spectrum disorders, due to impaired neuronal maturation.
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Actin-Like Protein 6B (ACTL6B) Antibody
ACTL6B Antibody is a Rabbit Polyclonal antibody against ACTL6B. The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
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Actin-Like Protein 6B (ACTL6B) Antibody
ACTL6B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
Ver Producto