Human Actin-Like Protein 6A (ACTL6A) ELISA Kit

Este producto es parte de ACTL - Actin Like
Human Actin-Like Protein 6A (ACTL6A) ELISA Kit
715€ (96 tests)

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Name
Human Actin-Like Protein 6A (ACTL6A) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx156869
Tested Applications
ELISA

Description

Human Actin-Like Protein 6A (ACTL6A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Actin Like Protein 6A (ACTL6A/BAF53A) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Actin-Like Protein 6A (ACTL6A)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
O96019
Alias
ACTL6,ARPN-BETA,Arp4,BAF53A
Background
Elisa Kits for: ACTL6A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

ACTL6A, also known as BAF53A, is a core component of the SWI/SNF chromatin remodeling complex. It interacts with actin-related proteins and histone modifiers to regulate transcriptional activity and chromatin structure. ACTL6A plays a pivotal role in neural development and stem cell maintenance. Structurally, ACTL6A contains an actin-like ATP-binding domain but does not form filaments like traditional actin. Instead, it stabilizes SWI/SNF complexes, enabling precise control over gene expression during differentiation. Mutations or overexpression of ACTL6A have been linked to cancers, particularly gliomas and squamous cell carcinoma, due to its role in regulating proliferation-related genes.

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