Human Actin Gamma 2, Smooth Muscle (ACTg2) Protein

Este producto es parte de ACTG - Actin Gamma
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Actin Gamma 2, Smooth Muscle (ACTg2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166595
tested applications
WB, SDS-PAGE

Description

Human Actin Gamma 2, Smooth Muscle Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Actin Gamma 2, Smooth Muscle (ACTg2)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 45.3 kDa  Observed MW (SDS-PAGE): 45 kDa

Concentration: Prior to lyophilization: 500 µg/ml

Sequence Fragment: Glu3-Phe376

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ACT,ACTA3,ACTE,ACTL3,ACTSG,MMIHS5
Background
Protein ACTG2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ACTG2 encodes gamma-actin, a highly conserved cytoskeletal protein primarily expressed in smooth muscle cells. It plays a vital role in maintaining the structure and contractility of smooth muscle tissues in organs such as the gastrointestinal tract and bladder. As part of the actin family, ACTG2 contributes to cellular processes like motility, intracellular transport, and mechanical force generation. Mutations in ACTG2 have been associated with disorders such as visceral myopathy, characterized by severe dysfunction of smooth muscle contractility. This protein is essential for the proper functioning of muscle-based physiological activities and demonstrates high evolutionary conservation due to its critical cellular roles.

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