Human Actin, Gamma 2, Smooth Muscle (ACTG2) ELISA Kit

Este producto es parte de ACTG - Actin Gamma
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689€ (96 tests)

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935106861
info@markelab.com
name
Human Actin, Gamma 2, Smooth Muscle (ACTG2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150529
tested applications
ELISA

Description

Human Actin, Gamma 2, Smooth Muscle (ACTG2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Actin gamma 2, Smooth Muscle (ACTg2) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Actin Gamma 2, Smooth Muscle (ACTg2)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Actin, Gamma 2, Smooth Muscle (ACTG2)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
ACT,ACTA3,ACTE,ACTL3,ACTSG,MMIHS5
Background
Elisa kits for ACTG2
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ACTG2 encodes gamma-actin, a highly conserved cytoskeletal protein primarily expressed in smooth muscle cells. It plays a vital role in maintaining the structure and contractility of smooth muscle tissues in organs such as the gastrointestinal tract and bladder. As part of the actin family, ACTG2 contributes to cellular processes like motility, intracellular transport, and mechanical force generation. Mutations in ACTG2 have been associated with disorders such as visceral myopathy, characterized by severe dysfunction of smooth muscle contractility. This protein is essential for the proper functioning of muscle-based physiological activities and demonstrates high evolutionary conservation due to its critical cellular roles.

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Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.

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