Human Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2 Ac#) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2 Ac#) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500866
tested applications
ELISA
Description
Human Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2 Ac#) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 29 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9NR19 |
| Alias | ACAS2,ACECS,ACS,ACSA |
| Background | Elisa kits for ACSS2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACSS2 is a cytosolic and nuclear enzyme that catalyzes the activation of acetate into acetyl-CoA, playing a central role in lipid synthesis, histone acetylation, and energy metabolism. It is highly expressed in the liver, adipose tissue, and brain, where it contributes to diverse metabolic and regulatory processes. In the nucleus, ACSS2 provides acetyl-CoA for histone acetylation, influencing gene expression and cellular responses to environmental changes. In the cytoplasm, it supports lipogenesis and cholesterol synthesis by activating acetate for incorporation into fatty acids and sterols. ACSS2 also plays a role in cancer metabolism by providing acetyl-CoA to fuel biosynthetic pathways in rapidly proliferating cells. Dysregulation of ACSS2 has been implicated in cancer progression, metabolic syndromes, and neurodegenerative diseases, highlighting its critical function in integrating metabolic and epigenetic regulation.
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