Human Absent In Melanoma 1 (AIM1) Protein

Este producto es parte de CRYBG - Beta/gamma crystallin domain-containing protein
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234€ (10 µg)

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935106861
info@markelab.com
name
Human Absent In Melanoma 1 (AIM1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167100
tested applications
WB, SDS-PAGE

Description

Absent In Melanoma 1 Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Absent In Melanoma 1 (AIM1)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 28.6 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Pro1502-Met1719
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
CRYBG1,ST4,AIM1
Background
Protein CRYBG1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CRYBG1 is a protein containing the beta-gamma crystallin domain, which is characteristic of structural proteins involved in lens transparency and light refraction in the eye. However, CRYBG1 is expressed beyond the lens, in tissues like muscle and connective tissue, where it is believed to play a role in cytoskeletal organization and cellular stress response. It interacts with molecular chaperones, potentially helping maintain protein stability under stress conditions. Dysregulation of CRYBG1 has been linked to muscle degeneration, fibrosis, and other diseases involving cytoskeletal abnormalities. Emerging evidence also suggests it might have a role in modulating cellular responses to oxidative stress, but further studies are needed to confirm its precise biological and pathological roles.

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