Absent In Melanoma 1 (AIM1) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Absent In Melanoma 1 (AIM1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx128263
tested applications
WB, IHC, IF/ICC
Description
Absent In Melanoma 1 Antibody is a Rabbit Polyclonal against Absent In Melanoma 1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Absent In Melanoma 1 (AIM1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y4K1 |
| Alias | CRYBG1,ST4,AIM1 |
| Background | Antibody anti-CRYBG1 |
| Status | RUO |
Descripción
CRYBG1 is a protein containing the beta-gamma crystallin domain, which is characteristic of structural proteins involved in lens transparency and light refraction in the eye. However, CRYBG1 is expressed beyond the lens, in tissues like muscle and connective tissue, where it is believed to play a role in cytoskeletal organization and cellular stress response. It interacts with molecular chaperones, potentially helping maintain protein stability under stress conditions. Dysregulation of CRYBG1 has been linked to muscle degeneration, fibrosis, and other diseases involving cytoskeletal abnormalities. Emerging evidence also suggests it might have a role in modulating cellular responses to oxidative stress, but further studies are needed to confirm its precise biological and pathological roles.
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