Human Abelson Tyrosine-Protein Kinase 2 (ABL2) ELISA Kit
715€ (96 tests)
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Name
Human Abelson Tyrosine-Protein Kinase 2 (ABL2) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx385559
Tested Applications
ELISA
Description
Human Abelson Tyrosine-Protein Kinase 2 (ABL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 2 (ABL2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Abelson Tyrosine-Protein Kinase 2 (ABL2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P42684 |
| Gene ID | 27 |
| OMIM | 164690 |
| Alias | ABLL,ARG,ABL proto-oncogene 2 non-receptor tyrosine kinase,Abelson Tyrosine Protein Kinase 2 |
| Background | Elisa Kits for: ABL2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
ABL2, also known as ARG (ABL-related gene), is a non-receptor tyrosine kinase closely related to ABL1, with overlapping roles in regulating actin cytoskeleton remodeling, cell adhesion, and migration. ABL2 is localized predominantly in the cytoplasm and membrane structures, where it interacts with actin-binding proteins and cytoskeletal components to regulate cell shape and motility. It contains similar structural domains to ABL1, including SH2 and SH3 domains, a kinase domain, and actin-binding regions that enable its role in cytoskeletal organization and intracellular signaling. ABL2 is highly expressed in tissues involved in structural integrity and movement, such as neurons and fibroblasts. Dysregulation of ABL2 activity has been implicated in cancer metastasis and neuronal disorders, where altered cell motility and adhesion contribute to disease progression. ABL2's role in neuronal development and its involvement in cancer highlight its potential as a therapeutic target in both neurodegenerative diseases and oncology.
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