935106861
info@markelab.com
Precio
362.5€ (100 µl)
ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases.ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half.The human c-Abl and ABL2 genes are expressed ubiquitously.ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization.c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML).The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.
Primary Antibodies
Monoclonal
Human, Mouse
Abelson Tyrosine-Protein Kinase 2 (ABL2)
Mouse
Unconjugated
Liquid
ELISA, IF/ICC
Unpurified ascites.
Ascitic fluid containing 0.03% sodium azide.
100 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
ABL2
No
Shipped within 5-10 working days.
ABLL,ARG,ABL proto-oncogene 2 non-receptor tyrosine kinase,Abelson Tyrosine Protein Kinase 2
This product is for research use only.
Non-receptor tyrosine-protein kinase that plays an ABL1-overlapping role in key processes linked to cell growth and surv...
Precio a consultar
Ver másABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins...
362.5€ (100 µl)
Ver másABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases.ABL2 ...
362.5€ (100 µl)
Ver más