Human A-Kinase Anchor Protein 3 (AKAP3) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human A-Kinase Anchor Protein 3 (AKAP3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385684
tested applications
ELISA
Description
Human A-Kinase Anchor Protein 3 (AKAP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human A Kinase Anchor Protein 3 (AKAP3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | A-Kinase Anchor Protein 3 (AKAP3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O75969 |
| Gene ID | 10566 |
| OMIM | 604689 |
| Alias | Fibrousheathin I,AKAP-3 |
| Background | Elisa kits for AKAP3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AKAP3 is a sperm-specific scaffold protein essential for sperm motility and capacitation. It is highly enriched in the fibrous sheath of the sperm flagellum, where it anchors PKA and other signaling molecules to regulate flagellar function and cAMP signaling. AKAP3 interacts with cAMP-binding proteins, ensuring precise localization of PKA to facilitate phosphorylation events that drive sperm motility and hyperactivation. It is also involved in sperm capacitation, where cAMP signaling leads to biochemical and structural changes necessary for fertilization. AKAP3 mutations or deficiencies impair sperm motility, leading to asthenozoospermia and infertility. Its role in organizing energy production by anchoring mitochondrial proteins highlights its importance in maintaining ATP supply for sperm movement. AKAP3 is also studied as a potential biomarker for male infertility due to its exclusive expression in sperm cells.
Related Products
AKAP3 antibody
May function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction.
Ver ProductoAKAP3 antibody
May function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction.
Ver Producto
A-Kinase Anchor Protein 3 (AKAP3) Antibody
Rabbit polyclonal antibody against AKAP3 protein. Immunogen region is Internal.
Ver Producto