Human 5-hydroxytryptamine receptor 3D (HTR3D) ELISA Kit
715€ (96 tests)
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935106861
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name
Human 5-hydroxytryptamine receptor 3D (HTR3D) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500210
tested applications
ELISA
Description
Human 5-hydroxytryptamine receptor 3D (HTR3D) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human 5-hydroxytryptamine receptor 3D (HTR3D) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | 5-hydroxytryptamine receptor 3D (HTR3D) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q70Z44 |
| OMIM | 610122 |
| Alias | HTR3D,5HT3D,5-HT3D receptor |
| Background | Elisa kits for HTR3D |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
HTR3D is a lesser-known subunit of the 5-HT3 receptor family, which functions as a ligand-gated ion channel. HTR3D assembles with the HTR3A subunit to form functional receptor complexes but does not form channels independently. Its co-expression with HTR3A influences the conductance, ion permeability, and pharmacological characteristics of the receptor. HTR3D is primarily expressed in the gastrointestinal tract, particularly in the enteric nervous system, where it modulates serotonin-mediated functions such as nausea, vomiting, and bowel motility. Its role in pain processing and visceral hypersensitivity has made it an emerging target for irritable bowel syndrome (IBS) and other functional gastrointestinal disorders. Genetic polymorphisms in the HTR3D gene have been associated with altered responses to 5-HT3 receptor antagonists, indicating its importance in personalizing therapies for chemotherapy-induced nausea and vomiting (CINV) and other serotonin-related disorders. Further research into HTR3D's function and interactions may reveal its broader contributions to neurotransmission and pharmacological modulation.
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