Human 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) ELISA Kit
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Description
Human 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.09 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q99943 |
| Gene ID | 10554 |
| OMIM | 603099 |
| Alias | 1-AGPAT1,G15,LPAAT-alpha |
| Background | Elisa kits for AGPAT1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGPAT1 is a key enzyme in the phospholipid biosynthesis pathway, catalyzing the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA) by acylating the sn-2 position of LPA. Structurally, AGPAT1 is an integral membrane protein localized to the endoplasmic reticulum (ER), where it participates in the synthesis of phospholipids and triglycerides. It plays an essential role in cell membrane formation, lipid signaling, and energy storage. AGPAT1 is ubiquitously expressed and is critical for maintaining cellular lipid homeostasis. Dysregulation of AGPAT1 is associated with metabolic disorders and diseases linked to impaired phospholipid metabolism, such as insulin resistance and lipodystrophy.
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