1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Antibody

Name: 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Antibody
Brand: Abbexa
SKU: abx004997
Price: 195 EUR
Availability: OnlineOnly

Este producto es parte de AGPAT - 1-acyl-sn-glycerol-3-phosphate acyltransferase

Pida mas información

935106861

info@markelab.com

Precio

195€ (20 µl)

Antibody anti-AGPAT1

proveedor

Abbexa

reference

abx004997

Tested Applications

ELISA, WB, IP

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

AGPAT1 Antibody is a Rabbit Polyclonal antibody against AGPAT1. This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.

Background

AGPAT1 is a key enzyme in the phospholipid biosynthesis pathway, catalyzing the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA) by acylating the sn-2 position of LPA. Structurally, AGPAT1 is an integral membrane protein localized to the endoplasmic reticulum (ER), where it participates in the synthesis of phospholipids and triglycerides. It plays an essential role in cell membrane formation, lipid signaling, and energy storage. AGPAT1 is ubiquitously expressed and is critical for maintaining cellular lipid homeostasis. Dysregulation of AGPAT1 is associated with metabolic disorders and diseases linked to impaired phospholipid metabolism, such as insulin resistance and lipodystrophy.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IP

purification

Purified by affinity chromatography.

recommended dilution

ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

size 1

20 µl

size 2

100 µl

size 3

2 × 100 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

AGPAT1

dry ice

availability

Shipped within 5-10 working days.

alias

1-AGPAT1,G15,LPAAT-alpha

uniprot id

https://www.uniprot.org/uniprotkb/Q99943

gene id

https://www.ncbi.nlm.nih.gov/gene/10554

NCBI accession

NP_006402.1

note

Concentration: > 0.2 mg/ml -

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anti- AGPAT1 antibody

proveedor

FineTest

reference

FNab00215

Tested Applications

ELISA, IHC, IP

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Converts lysophosphatidic acid(LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the g...

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