1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Antibody
357.5€ (100 µg)
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Name
1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx038261
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the AGPAT1 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Immunogen: Recombinant fragment corresponding to 82-283 AA of human AGPAT1. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 32 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_032741 |
| Alias | 1-AGPAT1,G15,LPAAT-alpha |
| Background | Antibody anti-AGPAT1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AGPAT1 is a key enzyme in the phospholipid biosynthesis pathway, catalyzing the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA) by acylating the sn-2 position of LPA. Structurally, AGPAT1 is an integral membrane protein localized to the endoplasmic reticulum (ER), where it participates in the synthesis of phospholipids and triglycerides. It plays an essential role in cell membrane formation, lipid signaling, and energy storage. AGPAT1 is ubiquitously expressed and is critical for maintaining cellular lipid homeostasis. Dysregulation of AGPAT1 is associated with metabolic disorders and diseases linked to impaired phospholipid metabolism, such as insulin resistance and lipodystrophy.
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