HTR5B Antibody
52€ (10 µg)
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935106861
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name
HTR5B Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015214
tested applications
ELISA, WB, IF/ICC
Description
Rabbit polyclonal antibody against HTR5B protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | HTR5B |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, IF/ICC: 1/100 - 1/500, ELISA: 1/40000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P35365 |
| Alias | HTR5B,5-Ht5b,5-HT5B receptor |
| Background | Antibody anti-HTR5BP |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
HTR5B (HTR5BP), designated as a pseudogene, is a non-functional gene closely related to the 5-hydroxytryptamine receptor 5A (HTR5A). Pseudogenes arise from functional ancestral genes through processes such as gene duplication or retrotransposition, resulting in a copy that has lost its ability to produce a functional protein. HTR5B retains significant sequence similarity to HTR5A, but it harbors mutations, insertions, or deletions that disrupt its open reading frame, rendering it non-coding. Despite its non-functional nature, HTR5B provides valuable evolutionary insight into the development and diversification of serotonin receptors within the genome. Pseudogenes like HTR5B can occasionally influence gene regulation by acting as decoys for transcription factors, participating in RNA-mediated regulation, or serving as sources of non-coding RNA. Understanding HTR5B contributes to a broader exploration of the serotonergic system and its role in neurobiology. Although it does not encode a receptor protein, HTR5B exemplifies the genomic plasticity underlying serotonin receptor evolution and highlights the complexity of non-coding genomic elements.
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