GULP1 Protein
234€ (5 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
GULP1 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx261038
tested applications
SDS-PAGE
Description
GULP1 is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | GULP1 |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q9UBP9 |
| Alias | GULP1,CED6,GULP,CED-6 |
| Background | Protein GULP1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
GULP1 is an adaptor protein containing a phosphotyrosine-binding (PTB) domain that mediates signal transduction in cell engulfment, phagocytosis, and apoptotic cell clearance. It interacts with transmembrane receptors like integrins and members of the engulfment pathway, including the CED-1 homologs. GULP1 facilitates actin cytoskeletal rearrangement by bridging receptors to downstream signaling proteins during phagosome formation. It is essential for apoptotic cell removal and has roles in cell migration and lipid homeostasis. GULP1 is expressed in macrophages, epithelial cells, and neurons, where it regulates tissue remodeling and cellular debris clearance. Dysregulation is linked to impaired phagocytosis, inflammatory diseases, and neurodegenerative disorders. Studies in knockout models highlight its role in maintaining immune homeostasis and preventing chronic inflammation.
Related Products
Human GULP1 (PTB domain-containing engulfment adapter protein 1) ELISA Kit
Ver Producto
anti- GULP1 antibody
May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
Ver Producto