GTF2I Repeat Domain Containing 1 (GTF2IRD1) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
GTF2IRD1 Antibody is a Rabbit Polyclonal antibody against GTF2IRD1. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GTF2I Repeat Domain Containing 1 (GTF2IRD1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UHL9 |
| Gene ID | 9569 |
| NCBI Accession | NP_057412.1 |
| Background | Antibody anti-GTF2IRD1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
Related Products

GTF2IRD1 antibody
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer(USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8(By similarity).
Ver Producto
GTF2I Repeat Domain Containing 1 (GTF2IRD1) Antibody
GTF2IRD1 Antibody is a Rabbit Polyclonal antibody against GTF2IRD1. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
Ver Producto
GTF2I Repeat Domain Containing 1 (GTF2IRD1) Antibody
Rabbit polyclonal antibody against GTF2IRD1 protein. Immunogen region is N-terminal.
Ver Producto