GTF2IRD1 antibody
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Description
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer(USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GTF2I repeat domain containing 1 (GTF2IRD1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 145 kDa, 120 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UHL9 |
| Gene ID | 9569 |
| Alias | General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1),General transcription factor III,MusTRD1/BEN,Muscle TFII-I repeat domain-containing protein 1,Slow-muscle-fiber enhancer-binding protein,USE B1-binding protein,Williams-Beuren syndrome chromosomal region 11 protein,Williams-Beuren syndrome chromosomal region 12 protein,GTF2IRD1,CREAM1,GTF3,MUSTRD1,RBAP2,WBSCR11,WBSCR12 |
| Background | Antibody anti-GTF2IRD1 |
| Status | RUO |
| Note | Mol. Weight 145 kDa, 120 kDa |
Descripción
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